When I first got Botox it didn’t do a goddamn thing – except paralyze my forehead. But after I’d gotten multiple rounds of injections over the course of 6-9 months, I saw real improvement in the intensity of my attacks. Now, there’s evidence showing that you could still expect big improvements from Botox even after your 3rd set of injections. Not only are those improvements then maintained if you keep up with injections, but there may even be additional improvements.

I tried Botox for the first time more than 15 years ago, then 4 years ago, but each time I only got one set of injections and then stopped after I saw no improvement in the first 3 months. Now I’ve been getting injections every 3 months for more than a year. I haven’t had my worst category of migraine in more than 6 months and I’m well enough to get out of bed and even eat during most migraines. 😀

So, if you’ve tried Botox and it didn’t work for you, try it again in 3 month increments for at least 6 months and then decide. Given it’s minimal side effects compared to other migraine preventative “treatments,” it’s probably worth a shot!

From Cephalalgia. 2016 Jun 10. pii: 0333102416652092.