I’ve been taking Petadolex for my migraines for 10 weeks now (The first week I wasn’t taking it). I’ve got 2 more weeks before I get to the 3 months mark – the amount of time it can take for the medicine to start working. I’ll be taking it for 2 or 3 weeks beyond the 12 week mark whether or not it appears to be working 1) for better data 2) because I have that many extra pills.